New aspects of TGF-β superfamily signaling in development and disease (2022 FASEB meeting review).
New aspects of TGF-β superfamily signaling in development and disease (2022 FASEB meeting review).
复制标题
DOI：
10.12703/r/11-36
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
第13届美国实验生物学学会联合会（FASEB）夏季研究会议于2022年7月在爱尔兰马拉海德大酒店召开，主题为“TGF-β超家族信号在发育和疾病中的作用”。转化生长因子-β (TGF-β)家族是在所有多细胞动物中发现的细胞间通讯因子。参加会议的是一群不同的学者，他们对理解TGF-β信号传导机制、正常功能以及与失调和突变相关的疾病有共同的兴趣。尽管在过去的35年里进行了大量的研究，TGF-β活性的新特征仍在不断被发现。这份会议报告提供了21个研究者提供的摘要，说明了发人深省的演讲的广度。会议的一个新主题是跨学科研究的力量，例如结合免疫学，生物化学和结构生物学，揭示寄生TGF-β模拟物的秘密。请参加我们下次的会议。
The 13th Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference, “TGF-β superfamily signaling in development and disease” was convened at the Grand Hotel in Malahide, Ireland in July 2022. The Transforming Growth Factor-β (TGF-β) family of secreted proteins consists of agents of intercellular communication found in all multicellular animals. Attending the meeting was a diverse group of scholars with shared interests in understanding TGF-β signaling mechanisms, normal functions, and the diseases associated with misregulation and mutation. Despite intense study over the previous 35 years, new features of TGF-β activity continue to be discovered. This meeting report offers 21 investigator-provided summaries that illustrate the breadth of the thought-provoking presentations. An emerging theme of the meeting was the power of cross-disciplinary studies, such as one combining immunology, biochemistry, and structural biology, to unravel the secrets of parasitic TGF-β mimics. Please join us at the next meeting.