Phylogenetic Trees Made Easy: A How-To Manual for Molecular Biologists
Phylogenetic Trees Made Easy: A How-To Manual for Molecular Biologists
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系统发育树变得简单：分子生物学家的操作手册
DOI：
10.1093/bib/3.4.429
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发表时间：
2002
影响因子：
9.5
通讯作者：
F. Wright
中科院分区：
文献类型：
--
作者：
F. Wright
系统发生树简化：分子生物学家操作手册巴里。Hall Sinauer Association Inc.马里兰州，美国;是执行摘要，“基因组的亮点”，从草案序列的主要发现.它说明了基因组中明显的信噪比有多小，并探讨了其冗余和重复的层次结构。它简要地看了细菌基因的水平转移的争议，并指出了序列草案如何已经和将被用于追踪与疾病有关的基因。一章的社论报价，标题和评论，从新闻界其次是一个很好的部分，探讨一些伦理法律的和社会问题，人类基因组带来了当前的相关性。这些包括法医测试和无罪证明、保险和隐私、体细胞和生殖细胞基因治疗、优生学、定制医学、专利和所有权。本章最后呼吁在遗传学、统计学和一般科学原则方面进行更广泛、更深入和更详细的教育，以便生物技术革命产生的信息得到利用，而不是滥用。
Phylogenetic Trees Made Easy: A How-To Manual for Molecular Biologists Barry G. Hall Sinauer Association Inc., Maryland, USA; IS executive summary,‘The highlights of the genome’, of the main findings from the draft sequence. It illustrates just how small is the apparent signal to noise ratio in the genome and explores its hierarchy of redundancy and duplication. It looks briefly at the controversy of the horizontal transfer of bacterial genes, and indicates how the draft sequence has been and will be used to track down the genes that are involved in disease.A chapter of editorialised quotes, headlines and comment from the press is followed by a good section exploring some of the Ethical Legal and Social Issues that the human genome brings into current relevance. These include forensic testing and the proof of innocence, insurance and privacy, somatic and germline gene therapy, eugenics, tailored medicine, patenting and ownership. This chapter ends with a plea for more widespread, deeper and detailed education in the principles of genetics, statistics and science in general, so that the information emerging from the biotechnology revolution is put to use, not misuse.