Helminth glycomics - glycan repertoires and host-parasite interactions
Helminth glycomics - glycan repertoires and host-parasite interactions
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DOI：
10.1016/j.molbiopara.2016.12.001
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发表时间：
2017-07-01
影响因子：
1.5
通讯作者：
van Diepen, Angela
中科院分区：
文献类型：
--
作者：
Hokke, Cornelis H.;van Diepen, Angela
寄生蠕虫的糖蛋白和糖脂在生物学和宿主-寄生虫相互作用中起着重要作用。这篇综述讨论了最近的蠕虫糖组学研究，扩大了我们的见解蠕虫的聚糖库。将结构数据与生物学和免疫学观察相结合，以突出糖组学如何促进我们对聚糖和聚糖基序在蠕虫感染生物学中发挥的关键作用的理解。展望了蠕虫糖组学和糖生物学的发展前景和面临的挑战。(C)2016爱思唯尔B. V.保留所有权利。
Glycoproteins and glycolipids of parasitic helminths play important roles in biology and host-parasite interaction. This review discusses recent helminth glycomics studies that have been expanding our insights into the glycan repertoire of helminths. Structural data are integrated with biological and immunological observations to highlight how glycomics advances our understanding of the critical roles that glycans and glycan motifs play in helminth infection biology. Prospects and challenges in helminth glycomics and glycobiology are discussed. (C) 2016 Elsevier B.V. All rights reserved.