Laterality of the olfactory event-related potential response.
Laterality of the olfactory event-related potential response.
复制标题
嗅觉事件相关潜在反应的偏侧性。
DOI：
10.1093/chemse/bjl011
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发表时间：
2006
期刊：
影响因子：
3.5
通讯作者：
Murphy,Claire
中科院分区：
文献类型：
--
作者：
Olofsson,JonasK;Broman,DanielA;Gilbert,PaulE;Dean,Pamela;Nordin,Steven;Murphy,Claire
在实验实践中，气味通常施加到只有一个嗅觉事件相关电位（OERP）的记录，但OERP反应的偏侧方面是不清楚的刺激的嗅觉和皮层地形。本研究的目的是调查是否刺激的右侧影响OERP的幅度和潜伏期，以及这些电位是否表明在健康的，右利手，年轻人的大脑反应偏侧化。在28名参与者中记录了9个电极部位对乙酸戊酯单嗅刺激的OERPs。结果表明，从额叶到顶叶电极部位（特别是N1/P3）的振幅普遍增加，左半球和中线的振幅普遍大于右半球。刺激侧对波幅无主效应。相互作用表明，N1/P2振幅是大的左比右右半球刺激和更大的左半球和中线比右半球在左半球刺激。未发现刺激侧与刺激侧之间的主效应或交互作用，也未发现刺激侧对矢状或冠状部位的刺激的主效应或交互作用。这些研究结果表明，一般顶叶，左半球的优势，气味刺激的反应幅度，并意味着无论是左或右丘脑可能是足够的准确评估OERP的潜伏期在右手，年轻的成年人。
In experimental practice, odors are commonly applied to only one nostril for recordings of olfactory event-related potentials (OERPs), but the lateralization aspect of the OERP response is unclear regarding both stimulated nostril and cortical topography. The purpose of the present study was to investigate whether stimulated-nostril side affects OERP amplitudes and latencies and whether these potentials indicate lateralization of brain response in healthy, right-handed, young adults. OERPs were recorded from nine electrode sites in response to monorhinal stimulation with amyl acetate in 28 participants. The results showed a general increase in amplitude from frontal to parietal electrode sites (in particular for N1/P3) and generally larger amplitudes on the left hemisphere and midline than on the right hemisphere. There was no main effect of stimulated-nostril side on amplitude. Interactions indicated that N1/P2 amplitude was larger for left- than right-nostril stimulation and larger on the left hemisphere and midline than on the right hemisphere in left-nostril stimulation. No main effect or interactions of stimulated-nostril side over latencies were found and no effects on latencies of sagittal or coronal sites. These findings suggest a general parietal, left-hemisphere predominance in response amplitude to odorous stimulation and imply that either the left or the right nostril may be sufficient for accurate assessment of OERP latency in right-handed, young adults.