An immediate-shock freezing deficit with discrete cues: A possible role for unconditioned stimulus processing mechanisms
An immediate-shock freezing deficit with discrete cues: A possible role for unconditioned stimulus processing mechanisms
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DOI：
10.1037/0097-7403.27.4.394
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发表时间：
2001-10-01
期刊：
影响因子：
--
通讯作者：
Abel, T
中科院分区：
文献类型：
--
作者：
Lattal, KM;Abel, T
Five experiments with C57BL/6 mice (Mus musculus) investigated whether failures in shock processing might contribute to deficits in freezing that occur after an animal receives a shock immediately on exposure to a conditioning context. Experiment 1 found that more contextual freezing resulted from delayed shocks than from immediate shocks across 4 shock intensities. Experiment 2 extended the immediate-shock freezing deficit to discrete stimuli. Experiment 3 found that preexposure to the to-be-conditioned cue did not facilitate immediate cued conditioning. Experiment 4 found that context preexposure enhanced context-evoked fear after an immediate shock. Experiment 5 found that context preexposure also enhanced immediate cued conditioning. These findings are problematic for current theories of the immediate-shock freezing deficit that focus exclusively on processing of the conditioned stimulus, and they suggest that failures in shock processing may contribute to the deficit.
