PRESSURE-SENSITIVE ION CHANNEL IN ESCHERICHIA-COLI
PRESSURE-SENSITIVE ION CHANNEL IN ESCHERICHIA-COLI
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DOI：
10.1073/pnas.84.8.2297
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发表时间：
1987-04-01
影响因子：
11.1
通讯作者：
KUNG, C
中科院分区：
文献类型：
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作者：
MARTINAC, B;BUECHNER, M;KUNG, C
我们用膜片钳记录技术对大肠杆菌的巨球形体进行了记录，发现了压力激活的离子通道。该通道具有以下性质：(I)被轻微的正负压激活；(Ii)电压依赖性；(Iii)大电导；(Iv)阳离子对阴离子的选择性；(V)活性与所指离子的种类的依赖性。我们认为这些通道可能参与了细菌的渗透调节和渗透趋化。
We have used the patch-clamp electrical recording technique on giant spheroplasts of Escherichia coli and have discovered pressure-activated ion channels. The channels have the following properties: (i) activation by slight positive or negative pressure; (ii) voltage dependence; (iii) large conductance; (iv) selectivity for anions over cations; (v) dependence of activity on the species of permeant ions. We believe that these channels may be involved in bacterial osmoregulation and osmotaxis.