Trans-synaptic Neural Circuit-Tracing with Neurotropic Viruses
Trans-synaptic Neural Circuit-Tracing with Neurotropic Viruses
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DOI：
10.1007/s12264-019-00374-9
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发表时间：
2019
影响因子：
5.6
通讯作者：
Lu Zhonghua
中科院分区：
文献类型：
--
作者：
Li Jiamin;Liu Taian;Dong Yun;Kondoh Kunio;Lu Zhonghua
A central objective in deciphering the nervous system in health and disease is to define the connections of neurons. The propensity of neurotropic viruses to spread among synaptically-linked neurons makes them ideal for mapping neural circuits. So far, several classes of viral neuronal tracers have become available and provide a powerful toolbox for delineating neural networks. In this paper, we review the recent developments of neurotropic viral tracers and highlight their unique properties in revealing patterns of neuronal connections.
