Testing for selection on the androgen-binding protein in the Danish mouse hybrid zone
Testing for selection on the androgen-binding protein in the Danish mouse hybrid zone
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DOI：
10.1111/j.1095-8312.2005.00446.x
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发表时间：
2005-03-01
影响因子：
1.9
通讯作者：
Boursot, P
中科院分区：
文献类型：
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作者：
Dod, B;Smadja, C;Boursot, P
家鼠的三个外周亚种具有固定的雄激素结合蛋白（ABP）的特定变体，这些变体被认为是参与亚种之间性隔离的识别机制的一部分。我们通过表征 Abpa 渗入穿过 M. m. 之间杂交区横断面的模式来测试对 Abpa 的选择。肌肉和 M. m。日德兰半岛的家蝇。在肌肉方面，Abpa 的序列比强烈选择的 X 和 Y 染色体标记更类似于近中性同种酶的序列。然而，将 Abpa 基因渗入尾部置换到更高频率的高中央步骤最好通过与针对杂种的强选择下的基因座的连锁来解释。尽管如此，我们不能排除这种模式是由于基因渗入尾部对 Abpa 的弱选择造成的，这与选型选择机制是兼容的。在家蝇方面，靠近混合区的地方几乎没有基因渗入，可能是由于地理上的迁移障碍。然而，肌肉等位基因的大量频率发生在更远的地方，表明混合的定植模式以及穿过混合区的流动。 (c) 2005 年伦敦林奈学会。
The three peripheral subspecies of the house mouse Mus musculus have fixed specific variants of the androgen-binding protein (ABP) that have been proposed to be part of a recognition mechanism that could participate in sexual isolation between the subspecies. We tested for selection on Abpa by characterizing the pattern of Abpa introgression across a transect of the hybrid zone between M. m. musculus and M. m. domesticus in Jutland. On the musculus side, the cline for Abpa resembled that of a nearly neutral allozyme more than that of strongly selected X and Y chromosome markers. However, the high central step which displaces the tail of introgression of Abpa to higher frequencies was best accounted for by linkage to a locus under strong selection against hybrids. Still, we cannot exclude that this pattern results from weak selection against Abpa in the tail of introgression, which would be compatible with an assortative choice mechanism. On the domesticus side there was little introgression close to the hybrid zone, presumably due to a geographical barrier to migration. However, substantial frequencies of musculus alleles occurred further away, suggesting mixed colonization patterns as well as flow across the hybrid zone. (c) 2005 The Linnean Society of London.