Deficiency syndrome of chronic gastritis
Deficiency syndrome of chronic gastritis
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发表时间：
1990-08
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影响因子：
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通讯作者：
Yang Cb;Tang Fk;Pan Xz
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作者：
Yang Cb;Tang Fk;Pan Xz
采用现代医学多指标临床研究方法，对161例慢性胃炎（其中浅表性胃炎59例，萎缩性胃炎86例，浅表性胃炎兼萎缩性胃炎16例）的脾虚证（其中脾虚证64例，脾肾两虚证97例）进行临床研究。选择胃镜图像、胃粘膜病理改变、胃钡餐检查、胃酸、血清胃泌素、尿胃蛋白酶原、尿17-酮类激素、植物神经功能、外周血象等作为观察指标。初步研究结果表明：脾虚证患者以浅表性胃炎为主，胃虚弱者占少数，胃液分泌量、血清胃泌素偏高，尿胃蛋白酶原、肾上腺皮质功能、血红蛋白偏低，而白色细胞较正常;而脾肾两虚者以萎缩性胃炎、胃虚为主，胃液分泌减少，血清胃泌素水平升高，而尿胃蛋白酶原、肾上腺皮质功能、白色细胞和血红蛋白偏低。在某些相同的炎症变化中，脾肾两虚证的胃液分泌量明显高于脾虚证。采用健脾益脾肾法治疗，各项指标均有相对改善。慢性胃炎的脾虚证和脾肾两虚证反映了胃粘膜炎症变化的严重程度和胃分泌功能的紊乱或失衡。提示其对造血功能及下丘脑-腺垂体-肾上腺皮质轴有影响。
: 161 cases of chronic gastritis (including 59 superficial gastritis, 86 atrophic gastritis, 16 superficial gastritis combined with atrophic gastritis) typed in deficiency syndrome (including 64 Spleen-deficiency syndrome, 97 Spleen-Kidney-deficiency syndrome) were studied clinically with modern medicinal multiple-index. The gastroscope image, pathologic changes of gastric mucosa, stomach barium meal examination, gastric acid, serum gastrin, urine pepsinogen, urine 17-ketosteroid, vegetative nerve function, peripheral blood picture, etc. were selected as observation indices. The preliminary findings showed that in Spleen-deficiency patients, the superficial gastritis constituted the majority, the asthenic stomach constituted the minority, the gastric secretion and the serum gastrin were on the high side, the urine pepsinogen, the adrenocortical function and the hemoglobin were on the low side, but the white blood cell was rather normal; otherwise, in Spleen-Kidney deficiency patients, the atrophic gastritis and the asthenic stomach constituted the majority, the gastric secretion decreased, the serum gastrin level was higher, while the urine pepsinogen, the adrenocortical function, white blood cell and the hemoglobin were on the low side. It was also found that in certain same inflammation changes, the gastric secretion of the Spleen-Kidney-deficiency syndrome was markedly than that of Spleen-deficiency syndrome. With the treatment method of invigorating the Spleen and reinforcing the Spleen-Kidney, each index was relatively improved. The degree of seriousness to inflammation changes of gastric mucosa and the disturbance or imbalance of gastric secretion function were reflected from the Spleen-deficiency and the Spleen-Kidney-deficiency syndromes of chronic gastritis. It is suggested that hemopoiesis and hypothalamo-adenohypophysial-adrenal cortical axis be influenced.