Chiroptical properties and racemization behavior of highly distorted donor-acceptor tetracyanoanthraquinodimethane with interconvertible planar chirality.
Chiroptical properties and racemization behavior of highly distorted donor-acceptor tetracyanoanthraquinodimethane with interconvertible planar chirality.
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DOI：
10.1002/chir.20427
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发表时间：
2008-03
期刊：
影响因子：
2
通讯作者：
H. Saito;Tadashi Mori;Y. Origane;T. Wada;Y. Inoue
中科院分区：
文献类型：
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作者：
H. Saito;Tadashi Mori;Y. Origane;T. Wada;Y. Inoue
通过圆二色谱（CD）的实验和理论计算，确定了具有可互变平面手性的光学活性7，12-双（二氰亚甲基）-7，12-二氢苯并[a]蒽（1）的绝对构型.在环境温度下静置后，发现1自发外消旋化，其速率通过手性HPLC在5-20 ° C下的分离曲线以及相同温度下的CD光谱衰减曲线进行评估。并对消旋机理进行了探讨。
Absolute configuration of optically active 7,12-bis(dicyanomethylene)-7,12-dihydrobenz[a]anthracene (1) with interconvertible planar chirality was determined by a comparison of experimental and theoretical circular dichroism (CD) spectra. Upon standing at ambient temperatures, 1 was found to spontaneously racemize, the rates of which were assessed through the separation profiles of chiral HPLC at 5-20 degrees C and also from the CD spectral decay profiles at the same temperatures. Mechanism of the racemization was discussed.