DNA probe detection of Eikenella corrodens, Wolinella recta and Fusobacterium nucleatum in subgingival plaque.
DNA probe detection of Eikenella corrodens, Wolinella recta and Fusobacterium nucleatum in subgingival plaque.
复制标题
DNA探针检测龈下菌斑中的腐蚀艾肯氏菌、直肠沃利氏菌和具核梭杆菌。
DOI：
10.1111/j.1399-302x.1991.tb00456.x
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发表时间：
1991
影响因子：
--
通讯作者：
French,CK
中科院分区：
文献类型：
--
作者：
Lippke,JA;Peros,WJ;Keville,MW;Savitt,ED;French,CK
这项横断面研究使用种属特异性DNA探针来检查龈下菌斑标本中是否存在腐蚀艾肯氏菌、直窝菌和具核梭杆菌，这些样本存在于未经治疗的牙周炎或牙龈炎成人和健康对照组中。直肠和F.牙周炎组病变部位核瘤的发生率明显高于对照组（分别为81%vs22%和83%vs20%）。62%的对照组和81%的牙周炎组中检测到腐蚀物。由于对照部位通常含有这种微生物，因此E.在区分健康和疾病时，腐蚀物可能没有用。此外，W.直肠和F.核瘤和确定的牙周病原体，放线放线杆菌伴放线菌，中间拟杆菌和牙龈拟杆菌的患病率进行了检查。W.直肠和F.核素与A的存在密切相关。actinomycetemcomitans、伴放线菌B.中间湾因此，W.直肠和F.牙周病的诊断和治疗都需要有足够的时间。
This cross‐sectional study used species‐specific DNA probes to examine subgingival plaque specimens for the presence of Eikenella corrodens, Wolinella recta, and Fusobacterium nucleatum in adults with untreated periodontitis or gingivitis and in healthy controls.W. rectaandF. nucleatumwere more prevalent in diseased sites from the periodontitis group when compared with the controls (81% vs 22% and 83% vs 20% respectively).E. corrodenswas detected in 62% of the control sites and 81% of the periodontitis sites. Because the control sites commonly contained this organism,E. corrodensmay not be useful in differentiating between health and disease. In addition, the relationship between the prevalence ofW. rectaandF. nucleatumand the prevalence of the established periodontal pathogens,Actinobacillus actinomycetemcomitans,Bacteroides intermediusandBacteroides gingivalis, was examined. Positive detection ofW. rectaandF. nucleatumcorrelated closely with the presence ofA. actinomycetemcomitans,B. intermediusandB. gingivalis.Therefore,W. rectaandF. nucleatumdo not appear to be unique indicators of periodontal disease.