Expression of a liver-specific function by a hepatoblastoma cell line cocultured with three-dimensional endothelialized tubes in collagen gels.
Expression of a liver-specific function by a hepatoblastoma cell line cocultured with three-dimensional endothelialized tubes in collagen gels.
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DOI：
10.1263/jbb.103.200
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发表时间：
2007-02
影响因子：
2.8
通讯作者：
T. Takei;S. Sakai;H. Ijima;K. Kawakami
中科院分区：
文献类型：
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作者：
T. Takei;S. Sakai;H. Ijima;K. Kawakami
人肝母细胞瘤细胞系Hep G2与胶原凝胶中的三维内皮化管共同培养时，显示出白蛋白产生活性，这是一种肝功能。以胶原蛋白为基础的肝样结构的白蛋白生成率随着结构中内皮化管长度的增加而增加。
A human hepatoblastoma cell line, Hep G2, showed albumin production activity, a hepatic function, when cocultured with three-dimensional endothelialized tubes in collagen gels. The albumin production rate of the collagen-based liver-like constructs increased with increasing length of the endothelialized tube in the construct.