Prevalence and features of intermittent explosive disorder in a clinical setting
Prevalence and features of intermittent explosive disorder in a clinical setting
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DOI：
10.4088/jcp.v66n1003
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发表时间：
2005-10-01
影响因子：
5.3
通讯作者：
Zimmerman, M
中科院分区：
文献类型：
--
作者：
Coccaro, EF;Posternak, MA;Zimmerman, M
目的：确定精神科门诊患者中DSM-IV间歇性爆发性精神障碍（IED）的寿命和当前患病率，沿着其他特征，如发病年龄、合并症模式和治疗兴趣。对轴I和11种疾病进行结构化诊断评估。结果：6.3%（SE，+/-0.7%）的患者符合终生DSM-IV IED诊断标准，3.1%（SE，+/-0.5%）的患者符合现行DSM-IV IED诊断标准。虽然只有0.6% +/- 0.2%的患者目前主要诊断为DSM-IV IED，但大多数目前患有DSM-IV IED的患者（80%）对治疗间歇性攻击行为感兴趣。与非IED患者相比，只有终生酒精/药物障碍在DSM-IV IED患者中更常见。发病年龄为DSM-IV IED达到高峰，在十几岁的时候，是男性比女性早，发生早于所有的共病障碍，与恐怖性焦虑障碍除外，这表明IED不能归因于大多数的共病conditions.Conclusions：精神病样本中的DSM-IV IED是远比以前认为的更常见。DSM-IV IED在生命早期发展，特别是在男性患者中，其发展可能独立于大多数其他疾病。
Objective: To determine the lifetime and current prevalence, along with other characteristics such as age at onset, patterns of comorbidity, and interest in treatment, of DSM-IV intermittent explosive disorder (IED) in an outpatient psychiatric sample.Method: 1300 individuals presenting for outpatient psychiatric treatment at Rhode Island Hospital, Providence, R.I., underwent structured diagnostic assessment for Axis I and 11 disorders. The diagnosis of IED was made according to DSM-IV criteria.Results: 6.3% (SE, +/- 0.7%) of patients met criteria for lifetime DSM-IV IED, and 3.1% +/- 0.5% of patients met criteria for current DSM-IV IED. While DSM-IV IED was the current principal diagnosis in only 0.6% +/- 0.2% of patients, most patients with current DSM-IV IED (80%) were interested in treatment for their intermittent aggressive behavior. Only lifetime alcohol/drug disorder was more frequent in DSM-IV IED compared with non-IED patients. Age at onset for DSM-IV IED peaked in the teen years, was earlier for men than women, and occurred earlier than all comorbid disorders, with the exception of phobic anxiety disorders, suggesting that IED cannot be attributed to most comorbid conditions.Conclusions: DSM-IV IED in psychiatric samples is far more common than previously thought. DSM-IV IED develops early in life, especially in male patients, and its development may be independent of most other disorders.