Ultrastructure and distribution of axon terminals from the reticular thalamic nucleus to the anteroventral thalamic nucleus of the rat.

Ultrastructure and distribution of axon terminals from the reticular thalamic nucleus to the anteroventral thalamic nucleus of the rat.
复制标题

大鼠网状丘脑核至丘脑前腹核轴突末端的超微结构和分布。

DOI:
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发表时间:
1996
期刊:
Journal fur Hirnforschung
影响因子:
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通讯作者:
K. Kishi
K. Kishi
中科院分区:
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文献类型:
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作者:
S. Oda;M. Kuroda;S. Chen;M. Shinkai;K. Kishi

文献摘要

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利用麦芽凝集素-辣根过氧化物酶(WGA-HRP)的顺行转运研究了从大鼠网状丘脑核(RTN)投射到丘脑前核(AV)的轴突末端的超微结构。在将 WGA-HRP 注射到 RTN 的内侧部分后,顺行标记的纤维分布在 AV 的腹侧和尾部,而在注射到 RTN 的背侧部分后,在丘脑前背核 (AD) 和 AV 的背侧部分发现了标记。主要标记末端为小到中等大小,含有多形性囊泡,并在广泛的神经元表面(包括细胞体、树突轴及其棘)上形成对称接触。大多数这些末端形成单个突触接触,而一些标记的末端在两个不同的突触后轮廓上有两个突触接触,例如在体细胞和大树突上、在体细胞和小树突上、在体细胞和树突棘上、以及在大树突和小树突上。
Ultrastructure of axon terminals projecting to the anterovetral thalamic nucleus (AV) from the reticular thalamic nucleus (RTN) of the rat was studied by using the anterograde transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP). Anterogradely labeled fibers were distributed in ventral and caudal parts in AV following WGA-HRP injections into the medial part of rostral RTN, whereas labelings were found in the anterodorsal thalamic nucleus (AD) and dorsal part of AV following injections into the dorsal part of rostral RTN. The main labeled terminals were small to medium in size, containing pleomorphic vesicles, and made symmetrical contacts on wide range of neuronal surfaces, including cell bodies, dendritic shafts and their spines. Majority of these terminals made a single synaptic contact, whereas some labeled terminals had two synaptic contacts on two different postsynaptic profiles, such as on both soma and large dendrite, on both soma and small dendrite, on both soma and dendritic spine, and on both large and small dendrites.