A profile of the cobas® TV/ MG test for the detection of Trichomonas vaginalis and Mycoplasma genitalium
A profile of the cobas® TV/ MG test for the detection of Trichomonas vaginalis and Mycoplasma genitalium
复制标题
用于检测阴道毛滴虫和生殖支原体的 cobas® TV/MG 测试概况
DOI：
10.1080/14737159.2020.1714440
复制
发表时间：
2020
影响因子：
5.1
通讯作者：
Barbara Van Der Pol
中科院分区：
文献类型：
--
作者：
Barbara Van Der Pol
摘要引言：阴道毛滴虫和生殖支原体是高度流行的性传播病原体，可能无症状或可能导致女性宫颈炎和盆腔炎以及男性尿道炎。由于缺乏诊断能力，我们对这些感染的流行病学了解有限，但在cobas® 6800/8800平台上运行的新cobas® TV/MG检测试剂盒为我们当前诊断能力的这一差距提供了解决方案。涵盖的领域：本文将描述我们所知道的流行病学和未经治疗的感染这些生物体的影响，以及目前的建议进行测试。将根据与该检测试剂盒相关的新数据描述cobas 6800/8800和TV/MG检测试剂盒的特征和性能。专家评论：需要可以在高通量系统上进行的毛滴虫和支原体的分子诊断，该系统具有仅订购所需测试的灵活性，以减少疾病负担和由这些病原体引起的未诊断感染的后果。由于在不同人群中进行测试的需求的复杂性，在测试排序中的样本特定的灵活性是分子实验室中的绝对需要。
ABSTRACT Introduction: Trichomonas vaginalis and Mycoplasma genitalium are highly prevalent sexually transmitted pathogens that may be asymptomatic or may cause cervicitis and pelvic inflammatory disease in women and urethritis in men. Our limited understanding of the epidemiology of these infections has been hampered by a lack of diagnostic capacity, but the new cobas® TV/MG assay runs on the cobas® 6800/8800 platform offers a solution to this gap in our current diagnostic capacity. Areas covered: This article will describe what we know about the epidemiology and impact of untreated infections with these organisms as well as current recommendations for testing. The features and performance of the cobas 6800/8800 and the TV/MG assay will be described based on the emerging data related to this assay. Expert commentary: Molecular diagnostics for trichomonas and mycoplasma that can be performed on a high-throughput system with the flexibility to order only those tests required are needed in order to reduce the burden of disease and of consequences of undiagnosed infections caused by these pathogens. As a result of the complexities in the needs for testing in different populations, sample-specific flexibility in test ordering is an absolute need in the molecular laboratory.
对临床标本中生殖支原体和大环内酯类耐药介导突变检测的实时 PCR 检测进行评估。
DOI：
10.1016/j.diagmicrobio.2018.02.002
发表时间：
2018
影响因子：
2.9
作者：
Xiao,Li;Waites,KenB;Wang,Hong;VanDerPol,Barbara;Ratliff,AmyE;Geisler,WilliamM
通讯作者：
Geisler,WilliamM