Preoperative risk factors for postoperative blood transfusion after hip fracture surgery: establishment of a nomogram.
Preoperative risk factors for postoperative blood transfusion after hip fracture surgery: establishment of a nomogram.
复制标题
髋部骨折术后输血的术前危险因素：线图的建立。
DOI：
10.1186/s13018-021-02557-5
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发表时间：
2021-06-23
影响因子：
2.6
通讯作者：
An YS
中科院分区：
文献类型：
--
作者：
Bian FC;Cheng XK;An YS
本研究旨在探讨髋部骨折手术前输血的相关危险因素，并建立诺模图预测模型。这种模式的应用将可能减少不必要的输血，避免浪费血液制品。这是对2013年1月至2020年1月接受髋部骨折手术的所有患者的回顾性分析。采用单因素和多因素Logistic回归分析方法，分析术前危险因素与髋部骨折术后输血的关系。最后，利用多元回归分析得到的危险因素建立诺模图模型。通过一致性指数（C指数）、受试者工作特征（ROC）曲线、决策曲线分析（DCA）和校准曲线评估诺模图的有效性。本研究共纳入820例患者进行评价。多因素Logistic回归分析显示，术前低血红蛋白（Hb）、全身麻醉（GA）、未使用氨甲环酸（TXA）、高龄是髋部骨折术后输血的独立危险因素。该模型的C指数为0.86（95% CI，0.83-0.89）。内部验证证明了诺模图模型的充分性和准确性，结果表明预测值与实际值吻合较好。基于髋部骨折术后输血的独立危险因素，建立了诺模图模型。术前干预可有效降低髋部骨折术后输血的发生率。
This study aimed to explore the preoperative risk factors related to blood transfusion after hip fracture operations and to establish a nomogram prediction model. The application of this model will likely reduce unnecessary transfusions and avoid wasting blood products. This was a retrospective analysis of all patients undergoing hip fracture surgery from January 2013 to January 2020. Univariate and multivariate logistic regression analyses were used to evaluate the association between preoperative risk factors and blood transfusion after hip fracture operations. Finally, the risk factors obtained from the multivariate regression analysis were used to establish the nomogram model. The validation of the nomogram was assessed by the concordance index (C-index), the receiver operating characteristic (ROC) curve, decision curve analysis (DCA), and calibration curves. A total of 820 patients were included in the present study for evaluation. Multivariate logistic regression analysis demonstrated that low preoperative hemoglobin (Hb), general anesthesia (GA), non-use of tranexamic acid (TXA), and older age were independent risk factors for blood transfusion after hip fracture operation. The C-index of this model was 0.86 (95% CI, 0.83–0.89). Internal validation proved the nomogram model’s adequacy and accuracy, and the results showed that the predicted value agreed well with the actual values. A nomogram model was developed based on independent risk factors for blood transfusion after hip fracture surgery. Preoperative intervention can effectively reduce the incidence of blood transfusion after hip fracture operations.
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影响因子：
2.6
作者：
Ye W;Liu Y;Liu WF;Li XL;Shao J
通讯作者：
Shao J
影响因子：
1.6
作者：
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Sawaguchi, Takeshi
影响因子：
1.1
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通讯作者：
Woolf, Shane K.
影响因子：
2
作者：
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通讯作者：
D'Agostino, RB
影响因子：
3
作者：
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通讯作者：
Chang, Kuang-Yi