UTE-T2(⁎) Analysis of Diseased and Healthy Achilles Tendons and Correlation with Clinical Score: An In Vivo Preliminary Study.
UTE-T2(⁎) Analysis of Diseased and Healthy Achilles Tendons and Correlation with Clinical Score: An In Vivo Preliminary Study.
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UTE-T2 患病和健康跟腱分析及其与临床评分的相关性：体内初步研究
DOI：
10.1155/2017/2729807
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发表时间：
2017
影响因子：
--
通讯作者：
Chen S
中科院分区：
文献类型：
--
作者：
Qiao Y;Tao HY;Ma K;Wu ZY;Qu JX;Chen S
Objective.采用三维超短回波时间（3D-UTE）序列，比较健康和病变跟腱（AT）的T2间期值，分析T2间期值与临床评分的相关性。方法.在3 T磁共振（MR）扫描仪上对10例有症状的跟腱患者和10例健康志愿者进行了3D-UTE序列检查。计算跟腱四个部位的T2时间。根据美国足踝矫形协会（AOFAS）评分和跟腱断裂评分（ATRS）评价患者的临床结局。采用独立样本t检验比较两组间T2间期值及临床评分的差异。评估临床评分和T2间期值之间的Pearson相关系数。结果患者与正常人跟腱T2间期值差异有统计学意义。患者的T2间期与AOFAS或ATRS评分之间的Pearson相关系数分别为r =-0.733和r =-0.634。结论健康和病理性AT中T2的变异性可以通过UTE-T2来量化。T2 T3可能是AT腱病的一个有前途的检测和诊断指标。结论：UTE-T2检测可准确指导临床疗效。
Objective. To compare T2⁎ value of healthy and diseased Achilles tendons (AT) with a recently introduced three-dimensional ultrashort echo time (3D-UTE) sequence and analyze the correlation between T2⁎ value and clinical scores. Methods. Ten patients with symptomatic Achilles tendon and ten healthy volunteers were investigated with 3D-UTE sequence on a 3T magnetic resonance (MR) scanner. T2⁎ values of four regions in Achilles tendons were calculated. The clinical outcomes of patients were evaluated according to the American Orthopaedic Foot and Ankle Society (AOFAS) score and Achilles Tendon Rupture Score (ATRS). An independent sample t-test was used to compare the differences of T2⁎ value and clinical scores between two groups. The Pearson correlation coefficient between clinical scores and T2⁎ values was assessed. Results. The T2⁎ values of Achilles tendon were statistically significantly different between patients and volunteers. The Pearson correlation coefficients between T2⁎ and AOFAS or ATRS scores of patients were r = −0.733 and r = −0.634, respectively. Conclusion. The variability of T2⁎ in healthy and pathologic AT can be quantified by UTE-T2⁎. T2⁎ may be a promising marker to detect and diagnose AT tendinopathy. UTE-T2⁎ could give a precise guidance to clinical outcome.