Alcoholic cardiomyopathy
Alcoholic cardiomyopathy
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DOI：
10.4330/wjc.v6.i8.771
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发表时间：
2014-08-26
影响因子：
1.9
通讯作者：
Garcia-Pavia, Pablo
中科院分区：
文献类型：
--
作者：
Guzzo-Merello, Gonzalo;Cobo-Marcos, Marta;Garcia-Pavia, Pablo
酒精是世界上最常见的有毒物质。研究表明，每天摄入少量至适量的酒精对心血管系统有有益的影响。相比之下，长期暴露于高水平的酒精可能会导致进行性心脏功能障碍和心力衰竭。与慢性和过量酒精摄入相关的心脏功能障碍是一种特定的心脏疾病，称为酒精性心肌病（ACM）。尽管它的临床重要性，关于ACM和酒精如何损害心脏的数据是有限的。在这篇综述中，我们评估了过量饮酒与心力衰竭和扩张型心肌病之间的联系。此外，我们还讨论了ACM的临床表现、预后和治疗。(C)2014百世登出版集团股份有限公司All rights reserved.
Alcohol is the most frequently consumed toxic substance in the world. Low to moderate daily intake of alcohol has been shown to have beneficial effects on the cardiovascular system. In contrast, exposure to high levels of alcohol for a long period could lead to progressive cardiac dysfunction and heart failure. Cardiac dysfunction associated with chronic and excessive alcohol intake is a specific cardiac disease known as alcoholic cardiomyopathy (ACM). In spite of its clinical importance, data on ACM and how alcohol damages the heart are limited. In this review, we evaluate available evidence linking excessive alcohol consumption with heart failure and dilated cardiomyopathy. Additionally, we discuss the clinical presentation, prognosis and treatment of ACM. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.