Fetal wound healing: Current biology
Fetal wound healing: Current biology
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DOI：
10.1007/s00268-002-6737-2
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发表时间：
2003-01-01
影响因子：
2.6
通讯作者：
Lorenz, HP
中科院分区：
文献类型：
--
作者：
Bullard, KM;Longaker, MT;Lorenz, HP
妊娠早期的胎儿皮肤创伤愈合迅速，不留疤痕。这种现象似乎是胎儿皮肤固有的，与宫内环境无关。胎儿细胞、细胞外基质、细胞因子谱和基因表达的独特性质有助于无疤痕修复。一项深入的研究工作集中在解开无瘢痕胎儿伤口愈合的机制，试图提高儿童和成人的愈合质量。
The early-gestation fetus heals dermal wounds rapidly and scarlessly. This phenomenon appears to be intrinsic to fetal skin and independent of the intrauterine environment. Unique properties of fetal cells, extracellular matrix, cytokine profile, and gene expression contribute to scarless repair. An intensive research effort has focused on unraveling the mechanisms that underlie scarless fetal wound healing in an attempt to improve the quality of healing in both children and adults.