OsREM4.1 Interacts with OsSERK1 to Coordinate the Interlinking between Abscisic Acid and Brassinosteroid Signaling in Rice
OsREM4.1 Interacts with OsSERK1 to Coordinate the Interlinking between Abscisic Acid and Brassinosteroid Signaling in Rice
复制标题
OsREM4.1 与 OsSERK1 相互作用，协调水稻中脱落酸和油菜素类固醇信号传导之间的相互联系
DOI：
10.1016/j.devcel.2016.06.011
复制
发表时间：
2016-07-25
影响因子：
11.8
通讯作者：
Li, Laigeng
中科院分区：
文献类型：
--
作者：
Gui, Jinshan;Zheng, Shuai;Li, Laigeng
植物激素之间的串扰对于平衡植物生长和适应各种环境至关重要。脱落酸（ABA）和油菜素类固醇（BR）在许多植物发育过程中表现出拮抗的相互作用，但人们对介导这些相互作用的分子机制知之甚少。在这里，我们鉴定了水稻 (Oryza sativa) remorin 基因 OsREM4.1，ABA 通过转录激活子 OsbZIP23 上调其表达。作为回报，OsREM4.1 负向调节 BR 信号输出。我们发现OsREM4.1与OsSERK1相互作用，抑制其与水稻BR受体OsBRI1的相互作用。此外，OsBRI1可以磷酸化OsREM4.1以降低OsREM4.1与OsSERK1的结合亲和力。这些结果表明，OsREM4.1 受 ABA 转录调节，并作为 OsBRI1 底物和 OsSERK1 相互作用蛋白发挥作用，抑制 OsBRI1-OsSERK1 受体复合物的形成和随后的激活。我们的研究结果深入了解了水稻中 ABA 和 BR 之间拮抗相互作用的协调机制。
Crosstalk among phytohormones is crucial for balancing plant growth and adjustment to various environments. Abscisic acid (ABA) and brassinosteroids (BRs) exhibit antagonistic interactions during many plant development processes, but little is known about the molecular mechanism mediating those interactions. Here, we identified a rice (Oryza sativa) remorin gene, OsREM4.1, whose expression is upregulated by ABA through the transcriptional activator OsbZIP23. OsREM4.1, in return, negatively regulates BR signaling output. We discovered that OsREM4.1 interacts with OsSERK1 to inhibit its interaction with rice BR receptor OsBRI1. Moreover, OsBRI1 could phosphorylate OsREM4.1 to reduce the binding affinity of OsREM4.1 to OsSERK1. These results demonstrate that OsREM4.1 is transcriptionally regulated by ABA and functions as an OsBRI1 substrate and OsSERK1-interacting protein to inhibit the formation and subsequent activation of the OsBRI1-OsSERK1 receptor complex. Our findings provide insight into the mechanism by which the antagonistic interactions between ABA and BRs are coordinated in rice.