Innovation - Healing sound: the use of ultrasound in drug delivery and other therapeutic applications
Innovation - Healing sound: the use of ultrasound in drug delivery and other therapeutic applications
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DOI：
10.1038/nrd1662
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发表时间：
2005-03-01
影响因子：
120.1
通讯作者：
Mitragotri, S
中科院分区：
文献类型：
--
作者：
Mitragotri, S
超声通常用于诊断成像应用，现在正被用于各种药物输送和其他治疗应用。超声已被证明可以促进药物通过皮肤的输送，促进基因治疗到目标组织，将化疗药物输送到肿瘤中，并将溶栓药物输送到血凝块中。此外，超声波也被证明可以促进伤口和骨折的愈合。本文就超声治疗的原理及现状作一综述。
Ultrasound, which is routinely used for diagnostic imaging applications, is now being adopted in various drug delivery and other therapeutic applications. Ultrasound has been shown to facilitate the delivery of drugs across the skin, promote gene therapy to targeted tissues, deliver chemotherapeutic drugs into tumours and deliver thrombolytic drugs into blood clots. In addition, ultrasound has also been shown to facilitate the healing of wounds and bone fractures. This article reviews the principles and current status of ultrasound-based treatments.