Comparison of PCR and Culture for Screening of Vancomycin-Resistant Enterococci: Highly Disparate Results for vanA and vanB
Comparison of PCR and Culture for Screening of Vancomycin-Resistant Enterococci: Highly Disparate Results for vanA and vanB
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DOI：
10.1128/jcm.01547-09
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发表时间：
2009-12-01
影响因子：
9.4
通讯作者：
Monczak, Yury
中科院分区：
文献类型：
--
作者：
Mak, Anton;Miller, Mark A.;Monczak, Yury
我们比较了PCR和传统培养在3年内检测30，835例直肠样本中万古霉素耐药肠球菌（VRE）的结果。vanB PCR阳性预测值为1.42%，阴性预测值为99.9%。通过PCR得到的阳性vanB结果预测性差，需要培养以区分VRE阳性和阴性个体。
We compared PCR to conventional culture for the detection of vancomycin-resistant enterococci (VRE) in 30,835 rectal samples over a 3-year period. The positive and negative predictive values of vanB PCR were 1.42% and 99.9%, respectively. A positive vanB result by PCR is poorly predictive and necessitates culture for differentiation of VRE-positive and -negative individuals.