Impact of the enzyme flexibility on the enzyme enantio-selectivity in organic media towards specific and non-specific substrates
Impact of the enzyme flexibility on the enzyme enantio-selectivity in organic media towards specific and non-specific substrates
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DOI：
10.1080/10242420290004938
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发表时间：
2002-08-01
影响因子：
1.8
通讯作者：
Broos, J
中科院分区：
文献类型：
--
作者：
Broos, J
A rationale is presented as to why the enantioselectivity of enzymes in dry organic media towards specific substrates is increased when the enzyme flexibility is increased. This is outlined for serine proteases towards N-acetyl-amino acid esters. The reasons why this relationship does not hold in the case of non-specific substrates are discussed.
