Structure of cytochromeb5unique to tardigrades
Structure of cytochromeb5unique to tardigrades
复制标题
缓步动物特有的细胞色素b5的结构
DOI：
10.1002/pro.3896
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发表时间：
2020
期刊：
影响因子：
8
通讯作者：
Inoue Tsuyoshi
中科院分区：
文献类型：
--
作者：
Fukuda Yohta;Kim JeeEun;Inoue Tsuyoshi
细胞色素b5是一种重要的电子传递蛋白，广泛存在于生命系统中，参与多种生物过程。迟滞(也被称为水熊)，其中一些以耐脱水而闻名，它们有许多独特的蛋白质。在这里，我们报道了一种来自耐脱水迟滞之一的类细胞色素b5蛋白(RvCytb5)的光谱和结构特征。1.4？分辨率的晶体结构表明RvCytb5是一种新的针对迟滞的细胞色素b5蛋白。
Cytochromeb5is an essential electron transfer protein, which is ubiquitously found in living systems and involved in wide variety of biological processes. Tardigrades (also known as water bears), some of which are famous for desiccation resistance, have many proteins unique to them. Here, we report spectroscopic and structural characterization of a cytochromeb5like protein from one of the desiccation‐tolerant tardigrades,Ramazzottius varieornatusstrain YOKOZUNA‐1 (RvCytb5). A 1.4 Å resolution crystal structure revealed thatRvCytb5is a new cytochromeb5protein specific to tardigrades.