Utility of the Social and Communication Questionnaire in the Differentiation of Autism from ADHD

Utility of the Social and Communication Questionnaire in the Differentiation of Autism from ADHD
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DOI:
10.1007/s10882-010-9199-8
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发表时间:
2010-08-01
影响因子:
1.8
通讯作者:
Ghaziuddin, Neera
Ghaziuddin, Neera
中科院分区:
医学4区
文献类型:
--
作者:
Ghaziuddin, Mohammad;Welch, Kathy;Ghaziuddin, Neera

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自闭症谱系障碍(ASD)和注意缺陷多动障碍(ADHD)经常同时发生。然而,由于自闭症患者经常出现多动和注意力不集中的症状,因此很难区分这两种情况。这篇文章的目的是确定社交与沟通问卷(SCQ)--一种常用的自闭症筛查工具--是否可以区分这两种情况。19名ASD参与者(17名男性;平均年龄10岁;SD 3.9)与57名ADHD参与者(43名男性;平均年龄8.4岁;SD 2.8)和22名ASD+ADHD参与者(19名男性;平均年龄9.2岁;SD 2.8)进行比较。ASD组与ADHD组之间差异有统计学意义(13.43vs7.08p<0.0001),而ASD组与ASD+ADHD混合组之间差异无统计学意义。多项回归分析发现,以下9个问题在区分自闭症和ADHD组方面特别重要:6、7、13、14、26、27、33、36和37。对这些发现的含义进行了讨论。
Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) often occur together. However, since symptoms of hyperactivity and inattention often occur in individuals with autism, distinguishing between the two conditions can be difficult. The purpose of this paper is to determine if the Social and Communication Questionnaire (SCQ), a commonly used screening measure for autism, can differentiate between the two conditions. Nineteen participants with ASD (17 males; mean age 10 years; SD 3.9) were compared with 57 participants with ADHD (43 males; mean age 8.4 years; SD 2.8); and 22 participants with ASD+ADHD (19 males; mean age 9.2 years; SD 2.8). Significant differences were found between the ASD and ADHD groups (13.43 versus 7.08, p < 0.0001) but not between the ASD and the mixed ASD+ADHD groups. A multinomial regression analysis identified the following nine questions as being especially important in differentiating between the ASD and ADHD groups: 6, 7, 13, 14, 26, 27, 33, 36 and 37. Implications of these findings are discussed.