Sequential Staudinger/Pictet-Spengler cyclization strategy for the construction of tetrahydroisoquinolines of the bioxalomycin and ecteinascidin family of alkaloids
Sequential Staudinger/Pictet-Spengler cyclization strategy for the construction of tetrahydroisoquinolines of the bioxalomycin and ecteinascidin family of alkaloids
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DOI：
10.1016/s0040-4039(00)02015-3
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发表时间：
2001-01-22
影响因子：
1.8
通讯作者：
Williams, RM
中科院分区：
文献类型：
--
作者：
Herberich, B;Kinugawa, M;Williams, RM
顺序使用Staudinger烯酮-亚胺S-内酰胺形成环加成反应和Pictet-Spengler环化反应，已用于制备与抗肿瘤生物碱的双曲霉素和海鞘素家族相关的高度官能化的四氢异喹啉。(C)2001年由Elsevier Science Ltd.出版
The use of the Staudinger ketene-imine S-lactam-forming cycloaddition reaction and the Pictet-Spengler cyclization reaction in sequence, has been used to prepare highly functionalized tetrahydroisoquinolines relevant to the bioxalomycin and ecteinascidin family of antitumor alkaloids. (C) 2001 Published by Elsevier Science Ltd.