Cortical activation associated with passive movements of the human index finger:: An MEG study

Cortical activation associated with passive movements of the human index finger:: An MEG study
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DOI:
10.1006/nimg.2001.1010
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发表时间:
2002-03-01
期刊:
影响因子:
5.7
通讯作者:
Hari, R
Hari, R
中科院分区:
医学1区
文献类型:
--
作者:
Alary, F;Simoes, C;Hari, R

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我们记录了8名健康成人的左右食指被动伸展的体感诱发场。设计了一种新的标定装置,可产生19 °的标定伸长,平均角速度为63 °/s。用306通道神经磁力计记录的反应用电流偶极子建模。最早的激活是在初级躯体感觉皮层,峰值分别在36-58和30-82 ms左右食指伸展。随后的信号在左侧第二躯体感觉(SII)皮层中观察到的8名受试者在75-175和75-155毫秒的左侧和右侧的扩展,分别有6名; 3名受试者显示双边SII激活至少在一个条件。我们的研究结果表明,人类左侧SII皮质在本体感受处理中的主导作用。(C)2002 Elsevier Science(美国)
We recorded somatosensory evoked fields to passive extensions of the left and right index fingers in eight healthy adults. A new nonmagnetic device was designed to produce calibrated extensions of 19degrees with a mean angular velocity of 63degrees/s. The responses, recorded with a 306-channel neuromagnetometer, were modeled with current dipoles. The earliest activation was in the primary somatosensory cortex, with peaks at 36-58 and 30-82 ms for left and right index finger extensions, respectively. Later signals were observed in the left second somatosensory (SII) cortex in six of eight subjects at 75-175 and 75-155 ms left- and right-sided extensions, respectively; three subjects showed bilateral SII activation in at least one condition. Our results suggest a predominant role for the human left SII cortex in proprioceptive processing. (C) 2002 Elsevier Science (USA)