Health and economic impact of HIV/AIDS on South African households: a cohort study.
Health and economic impact of HIV/AIDS on South African households: a cohort study.
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DOI：
10.1186/1471-2458-3-14
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发表时间：
2003-04-01
影响因子：
4.5
通讯作者：
Booysen FL
中科院分区：
文献类型：
--
作者：
Bachmann MO;Booysen FL
南非家庭受到人体免疫机能丧失病毒/后天免疫机能丧失综合症（艾滋病毒/艾滋病）的严重影响，但在对照组群研究中尚未量化健康和经济影响。我们比较了南非自由州省一个农村和一个城市地区有艾滋病毒感染成员的家庭和未受影响的邻居家庭。在基线和六个月后，在每个家庭中与一个关键的线人进行了访谈。我们研究了404个家庭的1913名成员，分别有94%和96%的随访。家庭和个人层面进行了分析。与未受影响的家庭成员相比，受影响的家庭成员更有可能持续患病（调整后的比值比（OR）2.1，95% CI 1.3-3.4）和死亡（调整后的OR 3.4，95% CI 1.0-11），主要是由于传染病。政府诊所和医院是保健的主要来源。受影响的家庭在基线时比未受影响的家庭贫穷（人均相对收入0.61，95% CI 0.49-0.76）。在六个月内，受影响家庭的支出和收入比未受影响家庭下降得更快（基线调整的相对支出为0.86，95% CI为0.75-0.99，收入为0.89，95% CI为0.75-1.05）。基线发病率与基线时较低的收入和支出独立相关，但与6个月内的变化无关。艾滋病毒/艾滋病影响到家庭和受感染者的健康和财富，加剧了原有的贫穷。
South African households are severely affected by human immunodeficiency virus / acquired immunodeficiency syndrome (HIV/AIDS) but health and economic impacts have not been quantified in controlled cohort studies. We compared households with an HIV-infected member, and unaffected neighbouring households, in one rural and one urban area in Free State province, South Africa. Interviews were conducted with one key informant in each household, at baseline and six months later. We studied 1913 members of 404 households, with 94% and 96% follow up, respectively. Household and individual level analyses were done. Members of affected households, compared to members of unaffected households, were independently more likely to be continuously ill (adjusted odds ratio (OR) 2.1, 95% CI 1.3–3.4 at follow up), and to die (adjusted OR 3.4, 95% CI 1.0–11), mainly due to infectious diseases. Government clinics and hospitals were the main sources of health care. Affected households were poorer than unaffected households at baseline (relative income per person 0.61, 95% CI 0.49–0.76). Over six months expenditure and income decreased more rapidly in affected than in unaffected households (baseline-adjusted relative expenditure 0.86, 95% CI 0.75–0.99 and income 0.89, 95% CI 0.75–1.05). Baseline morbidity was independently associated with lower income and expenditure at baseline but not with changes over six months. HIV/AIDS affects the health and wealth of households as well as infected individuals, aggravating pre-existing poverty.
影响因子：
120.7
作者：
Floyd, K;Reid, RA;Gilks, CF
通讯作者：
Gilks, CF
影响因子：
3.2
作者：
LANJOUW, P;RAVALLION, M
通讯作者：
RAVALLION, M
影响因子：
105.7
作者：
Vickers, AJ;Altman, DG
通讯作者：
Altman, DG