Kawasaki Disease With Particular Emphasis on Arterial Lesions
Kawasaki Disease With Particular Emphasis on Arterial Lesions
复制标题
特别强调动脉病变的川崎病
DOI：
--
复制
发表时间：
1991
期刊：
影响因子：
--
通讯作者：
N. Tanaka
中科院分区：
文献类型：
--
作者：
S. Naoe;Kei Takahashi;H. Masuda;N. Tanaka
川崎病（KD，或急性发热性皮肤粘膜淋巴结综合征（MCLS））于 1967 年首次由日本红十字会医疗中心的 Tomisaku Kawasaki 博士描述为一种临床实体。最初，人们认为它有良好的预后，但流行病学调查和病理学研究表明，它已被认为是一种常常致命的疾病。本报告首先介绍了川崎病的临床症状、历史背景、研究现状和流行病学问题，然后概述了川崎病的病理和形态学概述，重点关注血管的病理变化，以及这些变化与1）动脉炎的形态发生、2）冠状动脉瘤形成及其后遗症的机制和3）幼年动脉硬化的关系。
Kawasaki disease (KD, or acute febrile mucocutaneous lymph node syndrome (MCLS)) was first described as a clinical entity in 1967 by Dr. Tomisaku Kawasaki of the Japan Red Cross Medical Center. Originally, it was thought to have a favorable prognosis, but as epidemiological surveys, augmented by pathological studies, have shown, it has come to be recognized as an often fatal disorder. In this report, the clinical symptoms, historical background, present status of research and epidemiological problems of KD are first described, and then we present a pathological and morphological outline of KD, focusing on pathological changes in the blood vessels, and the relationships of these changes to 1) the morphogenesis of arteritis, 2) the mechanism of coronary artery aneurysm formation and its sequelae, and 3) juvenile arteriosclerosis.
影响因子：
158.5
作者：
NEWBURGER, JW;TAKAHASHI, M;MELISH, ME
通讯作者：
MELISH, ME