Comparison of methods for obtaining occupational exposure information in a case-control interview study

Comparison of methods for obtaining occupational exposure information in a case-control interview study
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病例对照访谈研究中获取职业暴露信息的方法比较

DOI:
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发表时间:
1986
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影响因子:
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通讯作者:
M. Szklo
M. Szklo
中科院分区:
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文献类型:
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作者:
Linet;W. Stewart;M. L. Natta;L. McCaffrey;M. Szklo

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病例对照访谈研究中职业暴露信息获取方法的比较。两种间接的方法,连接职业和行业的就业与特定的暴露和直接报告的职业暴露信息进行了比较,使用的数据,以人口为基础的病例对照访谈研究的慢性淋巴细胞白血病。使用Hoar等人开发的工作暴露矩阵和基于国家职业安全和健康研究所1972-1974年进行的国家职业危害调查收集的数据的联系系统,对怀疑与慢性淋巴细胞白血病风险增加有关的暴露进行了检查。两种职业暴露联系方法的暴露测定一致性差异很大。一般来说,相关性相当低,尽管对于所研究的某些接触(丁二烯和石棉,大多数kappas为0.40至0.60)来说,相关性要好于其他接触。对于四氯化碳和苯,这两种方法之间的相关性特别差(kappas范围为0.01至0.12)。较高比例的情况下,控制直接报告接触苯和石棉比确定使用两种更间接的方法,这两种方法都没有表现出一贯更大的相关性与直接报告。
Comparison of methods for obtaining occupational exposure information in a case-control interview study. Two indirect methods for linking occupation and industry of employment with specific exposures and directly reported occupational exposure information were compared using data from a population-based case-control interview study of chronic lymphocytic leukemia. Exposures suspected of being associated with increased risk of chronic lymphocytic leukemia were examined using a job-exposure matrix developed by Hoar et al. and a linkage system based on data collected in the National Occupational Hazard Survey conducted in 1972-1974 by the National Institute of Occupational Safety and Health. Concordance of exposure determination for the two occupation-exposure linkage methods was quite variable. In general, correlation was fairly low, although it was better for some of the exposures studied (butadiene and asbestos, for which most kappas were 0.40 to 0.60) than for others. Correlation between the two approaches was particularly poor for carbon tetrachloride and benzene (kappas ranged from 0.01 to 0.12). Higher proportions of cases and controls directly reported exposure to benzene and asbestos than was determined using the two more indirect methods, neither of which showed consistently greater correlation with direct reporting.