Empathic choice involves vmPFC value signals that are modulated by social processing implemented in IPL
Empathic choice involves vmPFC value signals that are modulated by social processing implemented in IPL
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DOI：
10.1093/scan/nsr086
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发表时间：
2013-02-01
影响因子：
4.2
通讯作者：
Rangel, Antonio
中科院分区：
文献类型：
--
作者：
Janowski, Vanessa;Camerer, Colin;Rangel, Antonio
同理心决策涉及代表他人做出选择，以最大限度地提高他们的福祉。例子包括父母为孩子做出的选择，以及政治家试图代表其选民做出正确选择的决定。我们使用人类功能磁共振成像任务研究了移情选择的神经生物学和计算基础，在该任务中，受试者用自己的钱为自己购买 DVD，或者用他人的钱为他人购买 DVD。我们发现，共情选择涉及腹内侧前额叶皮质的相同区域，这些区域已知用于计算刺激值，并且这些价值信号是由顶下小叶（IPL）区域的活动调节的，该区域已知在共情等社会过程中发挥着关键作用。我们还发现，用于做出移情选择的刺激值信号是使用自我模拟和他人模拟过程的混合来计算的，并且 IPL 中的活动编码了一个测量他人和自我偏好之间距离的变量，这为如何实现自我和他人模拟的混合提供了提示。
Empathic decision-making involves making choices on behalf of others in order to maximize their well-being. Examples include the choices that parents make for their children, as well as the decisions of a politician trying to make good choices on behalf of his constituency. We investigated the neurobiological and computational basis of empathic choice using a human fMRI task in which subjects purchased DVDs for themselves with their own money, or DVDs for others with the other's money. We found that empathic choices engage the same regions of ventromedial prefrontal cortex that are known to compute stimulus values, and that these value signals were modulated by activity from a region of inferior parietal lobule (IPL) known to play a critical role in social processes such as empathy. We also found that the stimulus value signals used to make empathic choices were computed using a mixture of self-simulation and other-simulation processes, and that activity in IPL encoded a variable measuring the distance between the other's and self preferences, which provides a hint for how the mixture of self-and other-simulation might be implemented.