Associations between daily living skills, cognition, and real-world functioning across stages of schizophrenia; a study with the Schizophrenia Cognition Rating Scale Japanese version.
Associations between daily living skills, cognition, and real-world functioning across stages of schizophrenia; a study with the Schizophrenia Cognition Rating Scale Japanese version.
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DOI：
10.1016/j.scog.2017.01.001
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发表时间：
2017-03
期刊：
影响因子：
--
通讯作者：
Suzuki M
中科院分区：
文献类型：
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作者：
Higuchi Y;Sumiyoshi T;Seo T;Suga M;Takahashi T;Nishiyama S;Komori Y;Kasai K;Suzuki M
精神分裂症谱系障碍患者的认知功能受损，即使在前驱期也是如此。具体而言，与日常生活功能或功能能力相关的认知能力评估对于预测长期结果非常重要。在这项研究中，我们试图确定精神分裂症认知评定量表（SCoRS）日文版的有效性，这是一种基于访谈的功能能力相关认知测量（即共同主要测量）。为此，我们研究了SCoRS分数与精神分裂症认知简明评估（BACS）日语版（一种标准神经心理学测试组合）和社会和职业功能评估量表（SOFAS）（一种基于访谈的社会功能量表）的表现之间的关系。本研究的受试者（n = 294）包括38例首发精神分裂症（FES）患者，135例慢性精神分裂症（CS）患者，102例高危精神状态（ARMS）患者和19例其他精神疾病伴精神病患者。SCoRS评分与整个受试者的SOFAS评分存在显著相关性。此外，BACS的表现与SCoRS评分显著相关。在每种诊断（FES、CS、ARMS）中也注意到这些相关性。这些结果表明，实用的SCoRS作为一种功能能力的措施，这是与认知功能和现实世界的功能结果与精神分裂症谱系障碍的主题。
Cognitive function is impaired in patients with schizophrenia-spectrum disorders, even in their prodromal stages. Specifically, the assessment of cognitive abilities related to daily-living functioning, or functional capacity, is important to predict long-term outcome. In this study, we sought to determine the validity of the Schizophrenia Cognition Rating Scale (SCoRS) Japanese version, an interview-based measure of cognition relevant to functional capacity (i.e. co-primary measure). For this purpose, we examined the relationship of SCoRS scores with performance on the Brief Assessment of Cognition in Schizophrenia (BACS) Japanese version, a standard neuropsychological test battery, and the Social and Occupational Functioning Assessment Scale (SOFAS), an interview-based social function scale. Subjects for this study (n = 294) included 38 patients with first episode schizophrenia (FES), 135 with chronic schizophrenia (CS), 102 with at-risk mental state (ARMS) and 19 with other psychiatric disorders with psychosis. SCoRS scores showed a significant relationship with SOFAS scores for the entire subjects. Also, performance on the BACS was significantly correlated with SCoRS scores. These associations were also noted within each diagnosis (FES, CS, ARMS). These results indicate the utility of SCoRS as a measure of functional capacity that is associated both with cognitive function and real-world functional outcome in subjects with schizophrenia-spectrum disorders.