Laryngeal tumor volume measurements determined with CT: A study on intra- and interobserver variability
Laryngeal tumor volume measurements determined with CT: A study on intra- and interobserver variability
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DOI：
10.1016/s0360-3016(97)00853-5
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发表时间：
1998-02-01
影响因子：
7
通讯作者：
Baert, AL
中科院分区：
文献类型：
--
作者：
Hermans, R;Feron, M;Baert, AL
目的：为了探讨内和观察者间的变异性的计算机断层扫描为基础的体积测量喉肿瘤，方法和材料：13喉肿瘤的体积重复测量5个独立的观察者在四个不同的会议，使用面积总和技术。计算每个肿瘤的平均肿瘤体积及其标准差。统计学分析采用方差分析、斯皮尔曼等级相关和线性回归分析。结果：观察者对肿瘤体积的影响（p < 0.0001）和疗程对肿瘤体积的影响（p < 0.01）均具有统计学意义。观察者间变异是总变异的最重要组成部分（89.3%）。平均体积和标准差之间存在显著的等级相关（p < 0.01）;平均肿瘤体积与标准差之间的关系可以使用线性回归来描述[标准差= 0.28体积+0.35（R = 0.79）]。基于计算机断层摄影的喉肿瘤体积测量的总可变性可以通过由单个受过训练的观察者进行测量来减少，（C）1998年Elsevier Science Inc.
Purpose: To investigate the intra-and interobserver variability of computed tomography-based volume measurements of laryngeal tumors,Methods and Materials: The volume of 13 laryngeal tumors was repeatedly measured by five independent observers in four different sessions, using the summation-of-areas technique. Mean tumor volume and its standard deviation mere calculated for each tumor. Statistical analysis was done with analysis of variance, Spearman rank correlation, and linear regression,Results: Both the effect of the observers (p < 0.0001) and the effect of the session (p < 0.01) on tumor volume was statistically significant. Interobserver variability was the most important component of total variability (89.3%). A significant rank correlation was found between mean volume and standard deviation (p < 0.01); the relationship between mean tumor volume and standard deviation can be described using linear regression [standard deviation = 0.28 volume + 0.35 (R = 0.79)].Conclusion: Total variability in the computed tomography-based measurement of laryngeal tumor volume can be reduced by having the measurements done by a single trained observer, (C) 1998 Elsevier Science Inc.