Acquired Superoxide-Scavenging Ability of Ceria Nanoparticles
Acquired Superoxide-Scavenging Ability of Ceria Nanoparticles
复制标题
二氧化铈纳米颗粒获得的超氧化物清除能力
DOI：
10.1002/anie.201410398
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发表时间：
2015-02-02
影响因子：
16.6
通讯作者：
Zhang, Zhiyong
中科院分区：
文献类型：
--
作者：
Li, Yuanyuan;He, Xiao;Zhang, Zhiyong
二氧化铈纳米粒子（纳米铈）是众所周知的超氧化物清除剂。然而，固有的超氧化物清除能力仅在尺寸小于5nm且形状多样性非常有限的纳米陶瓷中被发现。本文报道了一种显著提高尺寸大于5nm的纳米微球清除超氧化物活性的策略。尺寸大于5nm、形状不同、Ce3+/Ce4+比可以忽略不计的纳米陶瓷可以通过电子转移获得显著的超氧化物清除能力。该方法将使开发具有长效活性和可定制特性的纳米陶瓷基超氧化物清除剂成为可能。
Ceria nanoparticles (nanoceria) are well known as a superoxide scavenger. However, inherent superoxide-scavenging ability has only been found in the nanoceria with sizes of less than 5nm and with very limited shape diversity. Reported herein is a strategy to significantly improve the superoxide-scavenging activity of nanoceria sized at greater than 5nm. The nanoceria with sizes of greater than 5nm, with different shapes, and with a negligible Ce3+/Ce4+ ratio can acquire remarkable superoxide-scavenging abilities through electron transfer. This method will make it possible to develop nanoceria-based superoxide-scavengers with long-acting activity and tailorable characteristics.