RrgA and RrgB are components of a multisubunit pilus encoded by the Streptococcus pneumoniae rlrA pathogenicity islet
RrgA and RrgB are components of a multisubunit pilus encoded by the Streptococcus pneumoniae rlrA pathogenicity islet
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DOI：
10.1128/iai.74.4.2453-2456.2006
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发表时间：
2006-04-01
影响因子：
3.1
通讯作者：
Camilli, A
中科院分区：
文献类型：
--
作者：
LeMieux, J;Hava, DL;Camilli, A
肺炎链球菌TIGR4中的rlrA致病性胰岛编码三种表面蛋白RrgA、RrgB和RrgC以及三种分选酶。利用透射电子显微镜、细胞分级分离、细胞壁分选信号结构域交换和蛋白质印迹，我们证明了RrgA和RrgB被整合到S.肺炎。
The rlrA pathogenicity islet in Streptococcus pneumoniae TIGR4 encodes three surface proteins, RrgA, RrgB, and RrgC, and three sortase enzymes. Using transmission electron microscopy, cell fractionation, cell wall sorting signal domain swapping, and Western blotting, we show that RrgA and RrgB are incorporated into a multisubunit pilus in S. pneumoniae.