SENSITIVITY AND SPECIFICITY OF DEATH CERTIFICATE DIAGNOSES FOR DEMENTING ILLNESSES, 1988-1990
SENSITIVITY AND SPECIFICITY OF DEATH CERTIFICATE DIAGNOSES FOR DEMENTING ILLNESSES, 1988-1990
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DOI：
10.1111/j.1532-5415.1992.tb02015.x
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发表时间：
1992-05-01
影响因子：
6.3
通讯作者：
BRANDES, DA
中科院分区：
文献类型：
--
作者：
MACERA, CA;SUN, RKP;BRANDES, DA
目的：为了评估死亡率数据在多大程度上低估了痴呆症的患病率，死亡率数据通常用于跟踪特定疾病的长期趋势。设计：对现有数据进行回顾性分析。设置：南卡罗来纳州精神卫生部住院设施。受试者：在南卡罗来纳州全州阿尔茨海默病和相关疾病登记处列出的精神卫生部机构的住院患者，1988年和1990年（n = 450）。主要结果测量：死亡证明上的痴呆诊断的敏感性和特异性相比，医疗记录诊断为住院患者与生前dementia diagnosis.Results：23%的死亡证明包含任何痴呆诊断（104/450）。死亡证明的敏感性不同类型的痴呆症（28%的阿尔茨海默氏病，8%的多发性梗死性痴呆症），以及种族，性别和age.Conclusions：死亡率统计大大低估了痴呆症的患病率，并不完全代表痴呆症的公共卫生负担。
Objective: To evaluate the extent to which mortality data, which is often used to track secular trends for specific diseases, underestimates the prevalence of dementia.Design: Retrospective analysis of existing data.Setting: Department of Mental Health inpatient facilities in South Carolina.Subjects: Inpatients at Department of Mental Health facilities who were listed in the South Carolina Statewide Alzheimer's Disease and Related Disorders Registry and who died between 1988 and 1990 (n = 450).Main Outcome Measures: Sensitivity and specificity of dementia diagnoses on death certificates compared to medical record diagnoses for inpatients with a pre-mortem dementia diagnosis.Results: Twenty-three percent of death certificates contained any dementia diagnosis (104/450). The sensitivity of death certificates varied by type of dementia (28 percent for Alzheimer's disease; 8 percent for multi-infarct dementia) as well as by race, sex, and age.Conclusions: Mortality statistics substantially underestimate the prevalence of dementing illnesses and do not fully represent the public health burden of dementia.