Components of selection in X chromosome lines of Drosophila melanogaster: sex ratio modification by meiotic drive and viability selection.
Components of selection in X chromosome lines of Drosophila melanogaster: sex ratio modification by meiotic drive and viability selection.
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果蝇 X 染色体系选择的组成部分：通过减数分裂驱动和活力选择改变性别比例。
DOI：
10.1093/genetics/108.4.941
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发表时间：
1984
期刊：
影响因子：
3.3
通讯作者：
Curtsinger,JW
中科院分区：
文献类型：
--
作者：
Curtsinger,JW
在 18 个随机选择的携带野生 X 染色体的品系中估计了选择系数和分离参数。每个品系都在四种类型的重复杂交中进行了研究，每个杂交每个品系大约有 100 次重复。雄性X染色体不同的杂交表现出显着的性别比例异质性。分离参数的最大似然估计揭示了两条品系，其中雄性产生的带有X的配子的比例与孟德尔预期显着不同。这些观察结果表明，分离扭曲是自然发生的遗传变异的一个共同特征。非孟德尔分离具有重要的进化意义。
Selection coefficients and segregation parameters have been estimated in 18 randomly chosen lines carrying wildΧchromosomes on thecn bwgenetic background. Each line was studied in replicated crosses of four types, with approximately 100 replications per line per cross. Crosses in which maleΧchromosomes differed exhibited significant sex ratio heterogeneity. Maximum likelihood estimation of segregation parameters revealed two lines in which the proportion ofΧ-bearing gametes produced by males was significantly different from Mendelian expectations. These observations suggest that segregation distortion is a common feature of naturally occurring genetic variation. Non-Mendelian segregation has important evolutionary implications.