COMPARISON OF STRESS RESPONSE IN MALE AND FEMALE RATS - PITUITARY CYCLIC-AMP AND PLASMA PROLACTIN, GROWTH-HORMONE AND CORTICOSTERONE
COMPARISON OF STRESS RESPONSE IN MALE AND FEMALE RATS - PITUITARY CYCLIC-AMP AND PLASMA PROLACTIN, GROWTH-HORMONE AND CORTICOSTERONE
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DOI：
10.1016/0306-4530(83)90021-5
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发表时间：
1983-01-01
影响因子：
3.7
通讯作者：
MEYERHOFF, JL
中科院分区：
文献类型：
--
作者：
KANT, GJ;LENOX, RH;MEYERHOFF, JL
三种强效应激源（强迫跑步、固定和足部冲击）增加了雌性和雄性大鼠垂体中cAMP的水平。女性垂体cAMP反应与男性大体相似。测试的应激源升高血浆皮质酮和催乳素，降低血浆生长激素。应激后，血浆皮质酮在女性中比男性上升得更快。雄性大鼠的对照生长激素水平更高。垂体cAMP升高与血浆泌乳素、皮质酮和生长激素水平变化之间没有明确的因果关系。
Three potent stressors (forced running, immobilization and footshock) increased levels of cAMP in the pituitaries of both female and male rats. The pituitary cAMP response in females was generally similar to that observed in males. The tested stressors elevated both plasma corticosterone and prolactin, and decreased plasma growth hormone. Plasma corticosterone rose more rapidly in females than in males following stress. Control growth hormone levels were higher in male rats. There was no clear cause and effect relationship between elevations of pituitary cAMP and changes in plasma levels of prolactin, corticosterone, and growth hormone.