Myocardial perfusion and wall motion in infarction border zone: Assessment by myocardial contrast echocardiography
Myocardial perfusion and wall motion in infarction border zone: Assessment by myocardial contrast echocardiography
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DOI：
10.1016/s0894-7317(00)70004-6
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发表时间：
2000-05-01
影响因子：
6.5
通讯作者：
Picard, MH
中科院分区：
文献类型：
--
作者：
Scherrer-Crosbie, M;Liel-Cohen, N;Picard, MH
心肌梗死（MI）边界壁运动（WM）下降的几种机制已经提出，我们使用心肌超声造影（MCE）研究心肌梗死（MI）后6周5只羊梗死边界区（BZs）灌注与WM的关系。量化WM异常程度和灌注缺损程度后，定义为正常（NL）、梗死（梗死）和BZs。对比后的峰值强度以声单位（AU）测量。现在注射放射性标记微球来测量局部血液。心脏用2,3,5-三苯四唑氯（TTC）染色。MCE灌注缺损占心肌总面积的33% +/- 7%，与TTC有良好的相关性(r = 0.92， P
Several mechanisms have been proposed to explain the decreased wall motion (WM) at the borders of myocardial infarction (MI), We used myocardial contrast echocardiography (MCE) to Investigate the relation of perfusion to WM in infarcted border zones (BZs) 6 weeks after MI in 5 sheep. After quantifying the extent of WM abnormality and the perfusion defect, normal (NL), infarcted, and BZs were defined. Peak intensity after contrast was measured in acoustic units (AU). Radiolabeled microspheres were injected to measure regional blood now. The heart was stained with 2,3,5-triphenyltetrazolium chloride (TTC). The perfusion defect on MCE was 33% +/- 7% of the total myocardial area and correlated well with TTC (r = 0.92, P