Impact of maternal stress, depression and anxiety on fetal neurobehavioral development.

Impact of maternal stress, depression and anxiety on fetal neurobehavioral development.
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DOI:
10.1097/grf.0b013e3181b52df1
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发表时间:
2009-09
影响因子:
1.5
通讯作者:
Monk C
Monk C
中科院分区:
医学4区
文献类型:
--
作者:
Kinsella MT;Monk C

文献摘要

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虽然产后心理困扰已被广泛研究多年,尤其是产后抑郁症,但分娩后母亲抑郁、压力和焦虑的症状并不比怀孕期间更常见或更严重。本文综述了最新的研究,旨在确定妇女产前心理困扰对胎儿行为和儿童发育的影响,以及这种影响的生物学途径。这些研究与越来越多支持“胎儿起源假说”的文献一致,即产前环境暴露——包括母亲在子宫生理学中基于心理状态的改变——可以在整个生命周期中产生持续的影响。
While postnatal psychological distress has been widely studied for many years, particularly with a focus on postpartum depression, symptoms of maternal depression, stress, and anxiety are not more common or severe after childbirth than during pregnancy. This paper reviews the newer body of research aimed at identifying the effects of women’s antenatal psychological distress on fetal behavior and child development, and the biological pathways for this influence. These studies are in line with the growing body of literature supporting the “fetal origins hypothesis” that prenatal environmental exposures — including maternal psychological state–based alterations in in utero physiology — can have sustained effects across the lifespan.