Nafuredin, a novel inhibitor of NADH-fumarate reductase, produced by Aspergillus niger FT-0554
Nafuredin, a novel inhibitor of NADH-fumarate reductase, produced by Aspergillus niger FT-0554
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DOI：
10.7164/antibiotics.54.234
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发表时间：
2001-03-01
影响因子：
3.3
通讯作者：
Omura, S
中科院分区：
文献类型：
--
作者：
Ui, H;Shiomi, K;Omura, S
新化合物萘呋啶是一种厌氧电子传递（NADH-延胡索酸还原酶）抑制剂。从海绵中分离得到的尼日尔FT-0554的发酵液中分离得到，经光谱分析鉴定为环氧-δ-内酯，其烯基侧链甲基化。
A novel compound nafuredin, was isolated as an inhibitor of anaerobic electron transport (NADH-fumarate reductase). It was obtained from culture broth of Aspergillus niger FT-0554 isolated from a marine sponge, The structure was elucidated as an epoxy-delta -lactone with an attached methylated olefinic side chain on the basis of spectral analysis.