Jobs encompassing prolonged sitting in cramped positions and risk of venous thromboembolism: cohort study.
Jobs encompassing prolonged sitting in cramped positions and risk of venous thromboembolism: cohort study.
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DOI：
10.1258/shorts.2011.011121
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发表时间：
2012-02
影响因子：
--
通讯作者：
Gyntelberg F
中科院分区：
文献类型：
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作者：
Suadicani P;Hannerz H;Bach E;Gyntelberg F
越来越多的证据表明，长时间的空中旅行导致的长时间狭窄的坐姿会增加腿部深静脉血栓形成和肺栓塞的风险，即静脉血栓栓塞（VTE）。即使在与航空旅行无关的各种工作中，也可能发生长时间狭窄的坐姿，理论上，与VTE的风险增加有关。这个问题尚未解决。1997-2006年丹麦国家登记册动态队列研究（对入境和出境开放）。20-59岁的体力劳动者。该队列包括一个工作职能基本上以久坐为特征的暴露组（n = 105，564）和一个工作更有活力的对照组（n = 283，966）。丹麦。因肺栓塞和深静脉血栓形成导致的死亡和医院接触。与以动态体力活动为特征的职业相比，那些可能暴露于长时间坐在人体工程学不利位置的人群发生肺栓塞的风险显著更高（n = 77，相对风险1.28; 95%CI 0.97-1.67，单侧检验P = 0.04）。就深静脉血栓形成而言，他们的风险略高，但不显著（n = 256，相对风险1.09; 95% CI 0.94-1.26，P = 0.12）。尽管使用的方法不允许控制个体风险因素，但与具有更动态体力工作要求的社会经济可比组相比，包括较长和较短时间坐在潜在不利人体工程学位置（即狭窄坐姿）的职业具有更高的VTE风险。
There is mounting evidence that prolonged cramped sitting in connection with long-lasting air travel increases the risk of deep vein thrombosis of the legs and pulmonary embolism, i.e. venous thromboembolism (VTE). Prolonged cramped sitting may occur even in various jobs unrelated to air travel, and, theoretically, be associated with an increased risk of VTE. The issue is unsettled. A dynamic cohort study (open for both entry and departure) in Danish national registers 1997–2006. 20–59-year-old manual workers. The cohort consisted of an exposed group with job functions basically characterised as sedentary (n = 105,564) and a control group with more dynamic work (n = 283,966). Denmark. Deaths and hospital contacts due to pulmonary embolism and deep vein thrombosis. Compared with occupations characterized by dynamic physical activity, the group encompassing those who would potentially be exposed to prolonged sitting in ergonomically adverse positions, had a significantly higher risk of pulmonary embolism (n = 77, relative risk 1.28; 95% CI 0.97–1.67, P = 0.04 in one-sided test). With respect to deep vein thrombosis they had a slightly but not significantly higher risk (n = 256, relative risk 1.09; 95% CI 0.94–1.26, P = 0.12). Despite the crude method used allowing for no control of individual risk factors, occupations encompassing longer and shorter periods of sitting in potentially adverse ergonomic positions, i.e. cramped sitting, had a higher risk of VTE, than a socioeconomically comparable group with more dynamic physical work demands.