Plasma progesterone, FSH and LH levels associated with implantation in the mouse.
Plasma progesterone, FSH and LH levels associated with implantation in the mouse.
复制标题
血浆黄体酮、FSH 和 LH 水平与小鼠植入相关。
DOI：
10.1071/bi9770289
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发表时间：
1977
期刊：
影响因子：
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通讯作者：
A. GIDLEY‐BAIRD
中科院分区：
文献类型：
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作者：
A. GIDLEY‐BAIRD
在小鼠妊娠的前6天，每6小时测定一次血浆孕酮、LH和FSH。血浆孕酮和LH在第1天较低，最低值记录在性交后24小时。这两种激素的浓度在第2天的后半部分开始上升，在第3天继续上升，在第4天早期达到孕酮峰值25 ng/ml，在第4天晚期达到LH峰值37 ng/ml。孕酮水平下降，在第4天和LH在第5天，约一半的各自的峰值，然后保持相对恒定的测量期间的剩余部分。FSH水平在第1天早期较高（180 ng/ml），到中午急剧下降，当天晚些时候略有上升，随后在第2天下降至性交后48 h的最低水平2 ng/ml。第3天早些时候，FSH值升至120 ng/ml，然后在接下来的6小时内降至50-60 ng/ml，并在第4天和第5天保持在该水平相对稳定。这表明，LH与孕酮的产生和黄体的维持有关，而FSH与着床所需的雌激素的产生有关。
Measurement of plasma progesterone, LH and FSH were made every 6 h during the first 6 days of pregnancy in the mouse. Plasma progesterone and LH were low on day 1, minimum values being recorded at 24 h post coitus. Concentrations of both these hormones started rising during the second half on day 2 with the rise continuing during day 3 to a progesterone peak of 25 ng/ml early on day 4 and an LH peak of 37 ng/ml late on day 4. Levels of progesterone fell during day 4 and LH during day 5 to approximately half their respective peak values and then remained relatively constant over the remainder of the measurement period. Levels of FSH, which were high early on day 1 (180 ng/ml), fell sharply by midday with a small rise late in the day followed by a decline during day 2 to a minimum level of 2 ng/ml at 48 h post coitus. Early on day 3 FSH values rose to 120 ng/ml then fell to 50-60 ng/ml during the next 6 h and remained relatively stable at this level during days 4 and 5. It is suggested that LH is concerned with progesterone production and maintenance of the corpus luteum whilst FSH is concerned with the production of oestrogen required for implantation in this species.