Hemodynamic Responses to Exercise in Obese Children and Adolescents before and after Overweight Reduction
Hemodynamic Responses to Exercise in Obese Children and Adolescents before and after Overweight Reduction
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DOI：
10.1055/s-0028-1105927
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发表时间：
2009-07-01
影响因子：
1
通讯作者：
Reinehr, T.
中科院分区：
文献类型：
--
作者：
de Sousa, G.;Hussein, A.;Reinehr, T.
目的：探讨肥胖儿童减重前后分级踏车运动试验血流动力学参数的变化。42名肥胖儿童（平均年龄11岁）和40名健康，瘦儿童进行分级自行车运动测试（1、1.5、2、2.5W/kg），记录运动前（T1）、最大负荷时（T2）和运动结束后6 min（T3）的心率（HR）和血压（BP）。此外，还记录了每个斜坡内患者心率的增加（1-HR）和个体最大负荷（瓦特/kg）。在参与了一年的肥胖儿童门诊干预计划后，研究组再次接受了运动测试。结果：肥胖儿童T7、T2、T3收缩压均显著高于瘦儿童（P < 0.05），肥胖儿童T7、T2、T3收缩压均显著高于瘦儿童（P < 0.05），肥胖儿童T7、T2、T3收缩压均显著高于瘦儿童（P <0.05）。研究组的I-HR显著高于对照组（p < 0.05）。研究组在减重后T1、T2、T3时的HR、BP、血脂和胰岛素值均明显改善。结论：肥胖儿童的心血管系统运动能力明显低于消瘦儿童，在肥胖干预后，心血管系统运动能力得到改善。减轻超重对儿童肥胖的血流动力学和代谢变化有积极影响，从而改善心血管危险因素。
Objective: To determine the change of hemodynamic parameters in graded bicycle exercise testing in obese children before and after overweight reduction.Methods: Forty-two obese children (mean age 11 years) and 40 healthy, lean children underwent graded bicycle exercise testing (1, 1.5, 2, 2.5 Watt/kg) recording the heart rate (HR) and blood pressure (BP) before exercise (T1), at maximum load (T2), and 6 min after ending the exercise (T3). Furthermore, the increase of the patient's heart rate within each ramp (1-HR) and the individual maximum load (Watt/kg) were recorded. After participating in an one-year outpatient intervention program for obese children, the study group underwent exercise testing again. Furthermore, we analyzed the lipid and insulin levels in the study group before and after overweight reduction and correlated the changes of the hemodynamic parameters to the changes of the insulin and lipid levels.Results: The obese children had significantly (p < 0.05) higher systolic blood pressure values at T7, T2, and T3 as compared to the lean children. The I-HR was significantly (p < 0.05) higher in the study group. HR and BP at T1, T2, and T3, and the lipid and insulin values improved significantly in the study group after overweight reduction. The changes of HR and BP did not correlate to the changes of insulin and lipids.Conclusion: Compared to lean children, obese children demonstrated a significantly lower exercise capacity of the cardiovascular system, which improved after participating in an obesity intervention program. Overweight reduction influences the hemodynamic and metabolic changes of childhood obesity positively and thereby leads to an improvement of the cardiovascular risk factor profile.