Velocity Vector Imaging of Longitudinal Mechanical Properties of Upstream and Downstream Shoulders and Fibrous Cap Tops of Human Carotid Atherosclerotic Plaque
Velocity Vector Imaging of Longitudinal Mechanical Properties of Upstream and Downstream Shoulders and Fibrous Cap Tops of Human Carotid Atherosclerotic Plaque
复制标题
人颈动脉粥样硬化斑块上下游肩部和纤维帽顶部纵向力学特性的速度矢量成像
DOI：
10.1111/echo.12005
复制
发表时间：
2013-02-01
影响因子：
1.5
通讯作者：
Zhang, Mei
中科院分区：
文献类型：
--
作者：
Huang, Xiao-Zhen;Wang, Zhi-Yun;Zhang, Mei
目的：动脉粥样硬化斑块破裂与斑块本身的高局部机械应力密切相关。我们的目的是通过速度矢量成像（VVI）结合声密度测量（AD）成像来探索体内人体动脉粥样硬化斑块的上下游肩部和纤维帽顶部的纵向力学特性。方法和结果：我们纳入了 135 名颈动脉粥样硬化斑块患者。 VVI 和 AD 用于沿纵轴视图检查颈动脉斑块的 3 个区域。根据校正的平均图像强度 (AIIc%) < 或 50，总共 405 个区域被分类为低 AD 值或高 AD 值。上游的峰值收缩应变、应变率 (SR) 和速度显着大于下游肩部和颈动脉斑块的纤维帽顶部 (P
Aims: Atherosclerotic plaque rupture is closely related to high regional mechanical stress in the plaque itself. We aimed to explore the longitudinal mechanical properties of upstream and downstream shoulders and fibrous cap tops of human atherosclerotic plaques in vivo by velocity vector imaging (VVI) combined with acoustic densitometry (AD) imaging. Methods and Results: We included 135 patients with carotid atherosclerotic plaque. VVI and AD were used to examine 3 regions of carotid plaque along the longitudinal-axis view. A total of 405 regions were classified with low or high AD values by corrected averages image intensity (AIIc%) < or 50, respectively. Peak systolic strain, strain rate (SR), and velocity were significantly greater for upstream than downstream shoulders and fibrous cap tops of carotid plaque (P