Configurational assignment of rhizopodin, an actin-binding macrolide from the myxobacterium Myxococcus stipitatus

Configurational assignment of rhizopodin, an actin-binding macrolide from the myxobacterium Myxococcus stipitatus
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DOI:
10.1039/b810405k
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发表时间:
2008-01-01
影响因子:
4.9
通讯作者:
Menche, Dirk
Menche, Dirk
中科院分区:
化学2区
文献类型:
--
作者:
Horstmann, Nicole;Menche, Dirk

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38 元粘细菌聚酮化合物根足素(一种有效的肌动蛋白结合大环内酯)的相对和绝对立体化学通过基于 J 的构型分析结合分子建模和化学衍生化来确定。
The relative and absolute stereochemistry of the 38-membered myxobacterial polyketide rhizopodin, a potent actin-binding macrolide, was determined by J-based configurational analysis in combination with molecular modeling and chemical derivatization.