Experiments on the aortic arches in the chick

Experiments on the aortic arches in the chick
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DOI:
10.1002/ar.1090370302
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发表时间:
1928-01-01
期刊:
影响因子:
--
通讯作者:
Bremer, JL
Bremer, JL
中科院分区:
医学4区
文献类型:
--
作者:
Bremer, JL

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左第四主动脉弓的正常损失是由于机械力造成的。这些包括通过心脏下降将拱的腹侧端拉入心包腔,以及当处于该位置时,心管的螺旋扭转对拱的腹侧端的作用。扭转是雏鸡心脏所呈现的环的必然结果,并将左侧血管旋转至躯干的腹侧表面,从而导致其急剧弯曲。消失通常遵循这种不利的过程,但当需要容器时可以防止。实验结果是,心脏的心室被倒置,主干的螺旋完全展开。在这种情况下,左侧第四弓成为最终的主动脉弓,右侧作为颈背动脉的一部分降级到从属位置。这与哺乳动物的情况非常相似。
Normal loss of the left 4th aortic arch is due to mechanical forces. These include pulling down of the ventral ends of the arches into the peri-cardial cavity, by descent of the heart, and the action on them, when in this position, of the spiral torsion of the heart tube. The torsion is a necessary result of the loop assumed by the chick heart, and rotates the left vessel to the ventral surface of the trunk, thus causing it to bend sharply. Obliteration normally follows this disadvantageous course, but can be prevented when the vessel becomes necessary. As the result of experiment, the ventricles of the heart were inverted and the spiral of the common trunk completely unwound. Under these circumstances, the left 4th arch becomes the definitive aortic arch, the right being relegated to a subordinate position as a segment of the dorsal carotid artery. This is closely analogous to the condition in mammals.