BODY MASS INDEX VERSUS HEIGHT AND WEIGHT IN RELATION TO BLOOD PRESSURE FINDINGS FOR THE 10,079 PERSONS IN TEE INTERSALT STUDY
BODY MASS INDEX VERSUS HEIGHT AND WEIGHT IN RELATION TO BLOOD PRESSURE FINDINGS FOR THE 10,079 PERSONS IN TEE INTERSALT STUDY
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TEE 盐间研究中 10,079 人的体重指数与身高和体重与血压的关系
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
M. Shipley
中科院分区：
文献类型：
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作者：
A. Dyer;P. Elliott;M. Shipley
在INTERSALT（一项电解质和血压的国际研究）中，发现体重指数（kg/m2）与血压独立相关。这些关系在来自世界各地52个中心的10，079名年龄在20-59岁的男性和女性中进行了评估，基于标准化方案，观察员的中心培训，中心实验室和广泛的质量控制。本分析的目的是确定是否体重，身高直接调整，与血压密切相关的身体质量指数。对于所有男性和女性，调整年龄，性别，酒精摄入量，吸烟，钠和钾排泄量以及身高，血压与体重的偏相关系数分别为收缩压0.221和舒张压0.238。这些值略大于体重指数与血压的偏相关性，分别为0.215和0.229。尽管男性的体重指数与收缩压的回归系数大于女性，表明男性的收缩压与体重的关联更强，但体重直接调整身高的模型表明，男性和女性的收缩压差异与10 kg体重差异相关，均为3.0 mmHg。相应的体重相关舒张压差异范围从40-59岁女性的2.00 mmHg到20-39岁男性的2.7 mmHg。此外，在控制体重的情况下，身高与血压呈显著负相关。这些分析的结果支持使用体重，直接调整身高，作为一个有用的和实用的替代体重指数的肥胖与血压的关联分析。
In INTERSALT, an international study of electrolytes and blood pressure, body mass index (kg/m2) was found to relate independently to blood pressure. These relations were assessed in 10,079 men and women aged 20-59 years from 52 centers around the world, based on a standardized protocol, central training of observers, a central laboratory, and extensive quality control. The purpose of the present analyses was to determine whether weight, directly adjusted for height, related to blood pressure as strongly as did body mass index. For all men and women combined, with adjustment for age, sex, alcohol intake, smoking, and sodium and potassium excretion in addition to height, the partial correlations of blood pressure with weight were 0.221 for systolic blood pressure and 0.238 for diastolic blood pressure. These values were slightly larger than the partial correlations for body mass index with blood pressure, which were 0.215 and 0.229, respectively. Although the regression coefficients for body mass index with systolic pressure had been larger in men than in women, suggesting a stronger association of systolic pressure with weight in men, the models with weight directly adjusted for height indicated that the difference in systolic pressure associated with a 10-kg difference in weight was 3.0 mmHg in both men and women. The corresponding weight-associated diastolic pressure differences ranged from 2.00 mmHg in women aged 40-59 years to 2.7 mmHg in men aged 20-39. In addition, with control for weight, height had a significant inverse association with blood pressure. The results of these analyses support the use of weight, with direct adjustment for height, as a useful and practical substitute for body mass index in analyses of the association of adiposity with blood pressure.