SEROLOGIC FACTORS IN IDIOPATHIC DIFFUSE INTERSTITIAL PULMONARY FIBROSIS
SEROLOGIC FACTORS IN IDIOPATHIC DIFFUSE INTERSTITIAL PULMONARY FIBROSIS
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DOI：
10.1016/0002-9343(65)90207-x
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发表时间：
1965-01-01
影响因子：
5.9
通讯作者：
SILTZBACH, LE
中科院分区：
文献类型：
--
作者：
GOTTLIEB, AJ;SPIERA, H;SILTZBACH, LE
19例特发性弥漫性肺间质纤维化患者中，5例(27%)血清中有乳胶固定的巨球蛋白。4例伴有无法明确分类的一过性关节炎表现。在没有患类风湿性关节炎的患者的血清中也发现了类似的乳胶固定反应的发生率，这表明这一发现并不是针对任何一种疾病的。建议将对类风湿肺的诊断保留为肺纤维化和明确的类风湿性关节炎的罕见组合。
In 19 patients with idiopathic diffuse interstitial pulmonary fibrosis, the serum of 5 (27%) revealed latex-fixing macro-globulin. In 4 there were accompanying transient arthritic manifestations which were not readily classifiable. A comparable incidence of latex-fixing reactivity has been demonstrated in the serum of patients not afflicted with rheumatoid arthritis suggesting that this finding is not specific for any one disease. It is proposed that consideration of the diagnosis of rheumatoid lung be reserved for the rare combination of pulmonary fibrosis and unequivocal rheumatoid arthritis.