Trends in the incidence of ischaemic stroke in young adults between 1985 and 2011: the Dijon Stroke Registry
Trends in the incidence of ischaemic stroke in young adults between 1985 and 2011: the Dijon Stroke Registry
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DOI：
10.1136/jnnp-2013-306203
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发表时间：
2014-05-01
影响因子：
11
通讯作者：
Giroud, Maurice
中科院分区：
文献类型：
--
作者：
Bejot, Yannick;Daubail, Benoit;Giroud, Maurice
背景最近的数据表明，年轻人中风的发病率可能正在上升。在这项基于人群的研究中，我们的目的是确定过去三十年中55岁以下人群的中风发病率是否发生了变化。方法从基于人群的登记处前瞻性收集了1985年至2011年在法国第戎发生的所有首次中风病例（缺血性中风、自发性脑出血和未确定的中风）。计算发病率，并使用泊松回归估计发病率比（IRR），按年龄组和卒中亚型分析时间趋势。结果在27年的研究期间，4506例患者被记录（53%的女性，平均年龄74.6 +/- 14.4，10.1%年龄< 55岁）。注意到总体卒中发病率增加，55岁以下人群缺血性卒中发病率也增加（1994-2002年与1985-1993年的IRR为1.308; 95%CI为0.982 - 1.741，p=0.066，IRR为1.697; 95%CI为1.340 - 2.150，p
Background Recent data have suggested that stroke incidence in young people may be rising. In this population-based study, we aimed to determine whether the incidence of stroke in people aged < 55 years old had changed over the last three decades.Methods All cases of first-ever stroke (ischaemic stroke, spontaneous intracerebral haemorrhage, and undetermined stroke) occurring in Dijon, France, from 1985 to 2011 were prospectively collected from a population-based registry. Incidence rates were calculated and temporal trends were analysed by age groups and stroke subtypes using a Poisson regression to estimate incidence rate ratios (IRR). Risk factors and premorbid treatments were analysed.Results Over the 27-year study period, 4506 patients were recorded (53% women, mean age 74.6 +/- 14.4, 10.1% aged < 55 years). An increase in overall stroke incidence was noted, as was a rise in ischaemic stroke in individuals aged < 55 years (IRR 1.308; 95% CI 0.982 to 1.741, p=0.066 for period 1994-2002 vs period 1985-1993, and IRR 1.697; 95% CI 1.340 to 2.150, p